Wisepowder ine huwandu hwakazara hwezvinhu zvakagadzirwa zveKuchembera & Antiaging, uye ine huwandu hwese hwehutongi hwehurongwa.
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Kukwegura & Kukwegura (Anti-kuchembera)

Kukwegura chinhu chatinoita tese asi tinonzwisisa zvishoma kwazvo nezvazvo. Uropi hwako hunoita shanduko paunenge uchikwegura izvo zvinogona kuve nemhedzisiro pane yako ndangariro kana hunyanzvi hwekufunga Zviri nyore kuita runyorwa rwese shanduko dzinouya nezera - ndangariro kurasikirwa, makwinya, kurasikirwa kwemhasuru.
Kupisa (anti-kukweguru) inogona kuve nyaya yakaoma kutaura: hondo iri kurwiwa manje pamusoro pechinoreva izwi mukutsvagira nemushonga, uye sechinhu chechigadzirwa muzvigadzirwa zvinesimba uye zvinowanzo nyengedza.
Kurwisa (Anti-kuchembera) ikozvino kune zvakati wandei zvakasiyana kureva uye kutaurirana.
-Munharaunda yesainzi anti-kukweguru (antiaging) tsvakiridzo inoreva chete kunonoka, kudzivirira, kana kudzoreredza kuchembera. Ipo ramangwana rakatarisa zvakanyanya kuvimbisa, parizvino hapana hunyanzvi hwekuvhenekesa uye huripo hwehutano hunononoka kana kudzoreredza kuchembera muvanhu.
-Munzvimbo yekurapa uye ine mukurumbira bhizinesi nharaunda, anti-kuchembera mushonga zvinoreva kutanga kuona, kudzivirira, uye kurapwa kwezvirwere zvine chekuita nezera. Izvi zvakatosiyana nekugadzirisa kukwegura pachayo, uye nzira dzakasiyana siyana nemarapirwo aripo iye zvino. Semuenzaniso kurapwa kweAlzheimer, chirwere chinoenderana nekukwegura.
-Munharaunda yakakura yemabhizinesi - inosanganisira yakawanda yekunyepedzera kana yekunyepedzera kufambidzana - kurwisa kukwegura chiratidzo chakakosha uye nzira yakaratidzwa yekuwedzera kutengesa.

Antiaging upfu chikumbiro

Mune maitiro aya, zvigadzirwa zvinopesana nekukwegura zvava kuwedzera uye zvakakurumbira. Anti Anti poda application inosanganisira:
-Skin chengetedza zvigadzirwa
-Nutano hwehutano zvigadzirwa
-Freeal zvinwiwa
-Pharmaceutical chigadzirwa
Kuchembera & Alzheimer's kurapwa
Dementia inova yakajairika nezera. About 3% yevanhu vari pakati pemakore 65 ne74, 19% pakati pe75 ne84, uye vangangoita hafu yeavo vanopfuura makore makumi masere nemashanu ekuberekwa vane dementia. hosha dzechirwere cheAlzheimer, chirwere checebrovascular, chirwere cheParkinson uye chirwere chaLou Gehrig.
Kukwegura ndiyo njodzi huru yechirwere cheAlzheimer. Alzheimer's mhando ye dementia inokonzeresa matambudziko nekurangarira, kufunga uye maitiro. Zviratidzo zveAlzheimer zvinowanzo kukura zvishoma nezvishoma uye zvichitowedzera nekufamba kwenguva, zvichive zvakakura zvakakwana kuti zvipindire nemabasa ezuva nezuva. "Tinoziva kuti zera ndiro chinhu chikuru chinokonzera chirwere cheAlzheimer, saka hazvishamise kuti takawana chinodhaka chakanangana nekukwegura,"
FDA yakabvumidzawo seNamzaric, musanganiswa weNamenda (memantine) uye Aricept, kurapwa kwehuremu kusvika kune chirwere chechirwere cheAlzheimer.
Namendais (memantine) anotenda kushanda nekugadzirisa glutamate, anokosha brain kemikari. Kana zvikagadzirwa zvakawandisa, glutamate inogona kutungamira kuuropi hweseru. Nekuti NMDA vanopesana vanoshanda zvakasiyana kubva kune cholinesterase inhibitors, iyo mhando mbiri dzezvinodhaka dzinogona kuve dzakarongedzwa musanganiswa.
Zvigadzirwa zvitsva zvakawanda zvinozivikanwa kuti zvinobatsira pakurapa chirwere cheAlzheimer. Zvakadai seJ-147 powder, CMS121 powder.

Kurambidza kukaka zvigadzirwa zveupfu

J-147 poda (1146963-51-0): J147 chimwe chinhu chemushonga wemazuva ano wehupenyu, zvakaratidzirwa kurapa chirwere cheAlzheimer uye kudzoreredza kukwegura mumakonzo uye zvave kuda kugadzirira kuyedzwa kwekiriniki muvanhu. Chikwata ichi chiri kutoita zvimwe zvidzidzo pamamorekuru akachinjwa nemhedzisiro yaJ147 pa iyo mitochondrial ATP synthase-iyo pachayo inogona kunge iri nyowani zvinodhaka zvinodhaka. J147 yapedza iyo FDA-inodiwa toxicology kuyedza mumhuka.
Alpha-lipoic acid upfu (1077-28-7): Alpha-lipoic acid ikemikari yakaita sevhitamini inonzi antioxidant, zvinoreva kuti inogona kudzivirira kuuropi pasi pemamiriro ekukuvara kana kukuvara.
Alfa-lipoic acid inoita sekubatsira kudzivirira mamwe marudzi ekukuvara kwesero mumuviri, uye zvakare inodzosera Vitamini senge vitamini E nevhitamini C. Pane humbowo hwekuti alpha-lipoic acid inogona kuvandudza basa uye kufambiswa kwemauroni mune chirwere cheshuga.
Kurasikirwa nendangariro kunetsekana kunoitika pakati pevakuru vakuru .. Zvinotendwa kuti kukuvadzwa kubva kune oxidative kusagadzikana kunotamba chikamu chakakosha mukukanganwa kurangarira.
Nekuti alpha-lipoic acid ine simba antioxidant, zvidzidzo zvakaongorora kugona kwayo kudzora kufambira mberi kwezvinetso zvinoratidzirwa nekukanganwa kwendangariro, senge chirwere cheAlzheimer
Mbiriso, chiropa, itsvo, sipinashi, broccoli, uye mbatatisi zvinhu zvakanaka zvinopa alpha-lipoic acid.
CMS121 powder (1353224-53-9): Geroprotectors zvinhu zvine mukana wekudzora chiyero icho mhuka inosvika nekunongedza maitiro ekukwegura. Chidzidzo chitsva chinoongorora akati wandei emakomponi uye chinoratidza zvimwe zvinodzivirira mauroni kubva mukukuvara nekudzora kukwegura; ivo vaongorori vakatumidza aya macomputer geroneuroprotectors.
Nekushandisa makomisheni aya senheyo, vaongorori vakagadzira vatatu vaAlzheimer's drug drug vanodaidzwa kuti CMS121, CAD31, uye J147; ivo zvakare vakashandisa fisetin uye curcumin zvakananga. Chikwata chakaratidza kuti shanu dzese dzemakomputa idzi dzakaderedza biomarker yekukwegura, yakawedzera nzira yepakati yemakonzo nenhunzi, uye ndokudzora zviratidzo zvehuropi.

Kuitika kwekukwegura

Kuchembera ndiko kukanganisirwa kwenguva pane muviri wemunhu, uye kunoitika pane akawanda mazinga:
-Cellular kuchembera. Masero ezera zvichienderana nehuwandu hwenguva dzavakadzokorora. Sero rinogona kudzokorora kanosvika makumi mashanu nguva iyo genetic yezvinhu isati yagona kuteedzwa nenzira kwayo, izvo zvinokonzerwa nekufupiswa telomeres. Kukuvadza kwakanyanya kunoitwa kumasero nema free radicals uye zvimwe zvinhu, mamwe maseru anofanirwa kutevedzera.
-Hormonal kukwegura. Mahormoni anoita chinhu chikuru mukukwegura, kunyanya panguva yekukura kwemucheche uye kukura kwekuyaruka. Mahormone mazinga anochinja kuburikidza nehupenyu. Kukura kunounza acne uye hombe pores. Patinenge tichikura, kushanduka kwehomoni kunotungamira kune ganda rakaoma uye kuenda kumwedzi.
-Kwakakanganiswa kukuvara. Kukuvara kwakawedzerwa kwese kuri kunze. Kutaurwa nehupfu, zuva, zvikafu zvinokuvadza, kusvibiswa, uye utsi zvinotora muviri. Nekufamba kwenguva, izvi zvinhu zvekunze zvinogona kukonzera kukuvara kwetsitsi uye muviri unowira shure mukugona kwayo kuchengetedza nekugadzirisa maseru, tishu, uye nhengo.
-Metabolic kuchembera. Sezvo iwe uchienderera nezvezuva rako, masero ako anogara achichinja chikafu kuva simba, iyo inogadzira byproducts inogona kukuvadza. Maitiro ekugadzirisa uye kugadzira simba anoguma nekukuvara kwemuviri nekufamba kwenguva. Vamwe vanotenda kuti kudzikisa maitiro e metabolic kuburikidza nemaitiro akadai sekudzora calorie kunogona kunonoka kukwegura muvanhu.
Kazhinji hunhu hunhu hweAlzheimer's hunosanganisira kusarara, kudzungaira, kushushikana, kunetseka, kunetswa, kusagadzikana, uye kuora mwoyo. Masayendisiti ari kudzidza kuti sei zviratidzo izvi zvichiitika uye ari kudzidza kurapwa nyowani-zvinodhaka uye nondrug-kuzvibata.

Dheuteronomio:

  1. Mortimer RK, Johnston JR (1959). "Hupenyu Hurefu hweMunhu wega Mbiriso Masero". Zvisikwa. 183 (4677): 1751-1752. Bibcode: 1959Natur.183.1751M. doi: 10.1038 / 1831751a0. hdl: 2027 / mdp.39015078535278. PMID 13666896
  2. Ongororo yechirwere yakanangana nechirwere cheAlzheimer inoratidza kupokana nekukwegura ”(Press release). Salk Institute. 12 Mbudzi 2015. Yakadzorerwa Mbudzi 13, 2015.
  3. Vatsvakurudzi vanoona chinangwa chema molekyumu cheJ147, icho chave pedyo nemakiriniki ekurapa chirwere cheAlzheimer ”. Yakadzorerwa 2018-01-30.
  4. Correlation yeAlzheimer Disease Neuropathologic Shanduko Ine Cognitive Mamiriro: Kuongorora kweMabhuku Peter T. Nelson, Irina Alafuzoff, Eileen H. Bigio, Constantin Bouras, Heiko Braak, Nigel J. Cairns, Rudolph J. Castellani, Barbara J. Crain, Peter Davies, Kelly Del Tredici, Charles Duyckaerts, Matthew P. Frosch, Vahram Haroutunian, Patrick R. Hof, Christine M. Hulette, Bradley T. Hyman, Takeshi Iwatsubo, Kurt A. Jellinger, Gregory A. Jicha, Enikö Kövari, Walter A Kukull, James B. Leverenz, Seth Love, Ian R. Mackenzie, David M. Mann, Eliezer Masliah, Ann C. McKee, Thomas J. Montine, John C. Morris, Julie A. Schneider, Joshua A. Sonnen, Dietmar R. Thal, John Q. Trojanowski, Juan C. Troncoso, Thomas Wisniewski, Randall L. Woltjer, Thomas G. Gungwa J Neuropathol Exp Neurol. Munyori wechinyorwa; inowanikwa mu PMC 2013 Jan 30. Yakabudiswa mufomu yekupedzisira yakarongedzwa sa: J Neuropathol Exp Neurol. 2012 Chivabvu; 71 (5): 362--381. doi: 10.1097 / NEN.0b013e31825018f7

Zvinyorwa Zviri Kuitika